33432 - Chagas (T.cruzi) qPCR
Chagas disease, caused by the protozoan Trypanosoma cruzi, poses significant risks in transplant recipients due to potential transmission from donor organs or reactivation of a prior infection in recipients. The laboratory diagnosis of Chagas disease is challenging because the usefulness of different diagnostic tests will depend on the stage of the disease. Serology is the preferred method for patients in the chronic phase, whereas PCR can be successfully used to diagnose acute and congenital cases.
About Test
This assay is a sensitive and specific molecular diagnostic tool designed to detect Trypanosoma cruzi DNA in clinical specimens. This assay supports early diagnosis and monitoring of Chagas disease, particularly in high-risk populations such as transplant recipients, where timely detection is critical to preventing disease progression or reactivation.
ProcedureExtraction of T. cruzi DNA from specimen followed by amplification and detection using real-time, quantitative PCR. An internal control is added to ensure the extraction was performed correctly and the PCR reaction was not inhibited. This test has not been cleared or approved for diagnostic use by the U.S. Food and Drug Administration.
48 hours from time of receipt of sample.
| Specimen Type | Test Code | CPT Code | NY Approved | Volume | Assay Range | Special Instructions |
|---|---|---|---|---|---|---|
| whole blood | 33432 | 87799 | No | 2 mL (minimum 0.5mL) |
95 parasites/mL to 6.25E+08 parasites/mL |
|
Can be shipped at ambient temperature Monday through Friday.
Causes for RejectionSpecimens beyond their acceptable length of time from collection as listed in the specimen handling.
Specimens are approved for testing in New York only when indicated in the Specimen Information field above. The CPT codes provided are based on Eurofins Viracor’s interpretation of the American Medical Association's Current Procedural Terminology (CPT) codes and are provided for informational purposes only. CPT coding is the sole responsibility of the billing party. Questions regarding coding should be addressed to your local Medicare carrier. Eurofins Viracor assumes no responsibility for billing errors due to reliance on the CPT codes illustrated in this material.
Please note, this assay is not to be used for pre-transplant testing. For pre-transplant testing, please navigate to this page.