Video Part 4 - How Serum Biomarkers can Guide aGHVD Therapy: Results not matching up with GVHD, TMA (Thrombotic Microangiopathy) and COD
This video explores thrombotic microangiopathy (TMA) and its intricate relationship with acute graft versus host disease (aGVHD), shedding light on this important complication in transplant patients. It discusses the causes of complications of disease (COD) that can arise in these patients, emphasizing the need for effective monitoring. Key serum biomarkers used to monitor aGVHD are highlighted, illustrating how these markers can indicate disease severity and treatment response. The series also addresses the limitations of relying solely on clinical symptoms, noting that there can be significant mismatches between clinical findings and biomarker results. Factors contributing to these discrepancies are examined, underscoring the importance of integrating biomarker data into clinical practice for better patient management.
